Call details:

PRECISEU Open Call (Horizon Europe programme, Cascade Funding)

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Official call identifier: PRECISEU

Objective of the call

The PRECISEU Open Call aims to fund Joint Interregional Projects (JIPs) that accelerate the adoption and scale-up of personalised medicine solutions across Europe.

The call focuses on reducing fragmentation and inequalities in healthcare innovation, strengthening interregional collaboration, and supporting the development and deployment of advanced technologies in health ecosystems.

It also seeks to improve accessibility and affordability of personalised medicine, reinforce regional innovation capacity, and promote knowledge transfer between European regions.

Scope of activities 

The call supports deep-tech innovation activities in personalised medicine, focusing on experimental development at Technology Readiness Levels (TRL) 6 to 8.

Projects must contribute to increasing the maturity of technologies within this TRL range.

The scope is structured around two main areas:

• Advanced therapeutics
• Health data for personalised medicine

Eligible activities include:

• Scale-up activities addressing remaining scientific or technical uncertainty
• Optimisation and validation of analytical methods
• Development of in vivo, in silico or in vitro models
• Generation of evidence to resolve technical challenges
• End-user collaborative experimental development
• Regulatory-readiness activities linked to innovation pathways

Activities related to routine market deployment, commercial roll-out or distribution are not eligible.

Eligible applicants 

Eligible applicants are legal entities established in EU Member States or Horizon Europe Associated Countries (described in General Annex A, General Annex B, General Annex C).

Eligible organisations include:

• Companies (including SMEs and large companies)
• Research institutes and universities
• Technology centres
• Hospitals
• Public administrations
• Associations and NGOs (including patient organisations)
• Public and private research bodies

Consortium requirements:

• At least 3 independent legal entities
• Established in 3 different regions covered by participating Funding Agencies
• At least 2 entities from 2 different EU Member States
• At least 1 SME from a PRECISEU region
• All core partners must be eligible for funding

Geographical eligibility for funding (strict condition):

Financial support is ONLY available to applicants established in regions covered by participating PRECISEU Funding Agencies.

These regions include:

• Catalonia (Spain)
• Baden-Württemberg (Germany)
• Nord-Est (Romania)
• Emilia-Romagna (Italy)
• Castilla-La Mancha (Spain)
• Crete (Greece)
• Lazio (Italy)
• Lithuania
• Ireland

Important:

• Applicants from other PRECISEU regions or from EU / Associated Countries may participate in consortia but will NOT receive funding under this call
• Only entities from funding regions can act as consortium coordinators

Eligible costs 

The call applies a lump sum funding model.

Eligible cost categories include:

• Personnel costs
• Subcontracting (for complementary tasks)
• Travel and subsistence
• Equipment (depreciation)
• Other goods and services
• Indirect costs (calculated as 25% of eligible direct costs excluding subcontracting)

Funding conditions 

Type of action: 
Cascade Funding

Funding rate: 
• Up to 100% for non-profit legal entities
• Up to 70% for profit-making legal entities
• 0% for entities from non-funding regions (self-funded participation)

EU contribution per project: 
The maximum financial contribution per project is €3 000 000 (The amount of financial support varies based on the funding rate and is limited to a maximum of €600 000 per beneficiary.)

Project duration: 
From October 2026 to March 2029

Technology Readiness Level (TRL): 
Projects are expected to reach TRL 6-8 by the end of the project 

*Technology Readiness Levels (TRL) describe the maturity of a technology, from basic research (TRL 1) to fully deployed, market-ready solutions (TRL 9). TRL 6-8 corresponds to pilot-scale validation and demonstration in relevant operational environments.

Deadline for submission

10 July 2026

Open
Company size: SMEs, Startups, Enterprises, Research, Academia
Issuer: European Research Executive Agency
Area: Health, Personalised medicine
Call type: Cascade Funding
Co-funding: Up to 100%
Date published: 13 April 2026
Deadline for submission: 14 June 2026