Call details:

Microbiome for terrestrial livestock sustainability and health within a One Health approach (Horizon Europe programme)

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Official call identifier: HORIZON-CL6-2027-02-FARM2FORK-03

Objective of the call

The objective of this call is to advance microbiome research in terrestrial livestock systems to improve animal health, productivity, and sustainability within a One Health framework. It aims to generate knowledge, tools, and strategies that link animal, human, and environmental health, while reducing antimicrobial use and environmental impact.

Scope of activities

Projects should investigate livestock microbiomes and their interactions with animals, humans, and the environment. Activities include developing integrated monitoring systems, assessing microbiome-based solutions across soil, plant, and animal systems, and designing holistic health models. Proposals should develop intervention strategies to prevent disease transmission and reduce antimicrobial resistance, while improving animal welfare and productivity. Projects should also contribute to collaborative platforms for microbiome research and strengthen cross-disciplinary cooperation across relevant scientific and sectoral fields.

Eligible applicants 

  • Innovative SMEs, startups and enterprises aiming to scale and strengthen competitiveness 
  • Public-sector organisations driving transformation and societal impact 
  • Research and academic institutions commercialising knowledge 
  • Non-profit organisations delivering purpose-driven innovation 
  • Participation is limited to legal entities established in Member States, Iceland and Norway, associated countries, OECD countries and MERCOSUR countries. (described in General Annex A, General Annex B, General Annex C)
  • Minimum 3 independent partners from 3 eligible countries 

Specific consortium we are looking for:

Consortia should include microbiologists, veterinarians, geneticists, animal and plant biologists, epidemiologists, ecologists, and data scientists. Participation of livestock farmers, breeders, service providers, and industry stakeholders is expected to ensure real-world validation and implementation. Collaboration with experts in One Health, antimicrobial resistance, and zoonotic disease is essential, along with integration with existing EU-funded initiatives and partnerships.

Eligible costs 

Eligible costs will take the form of a lump sum contribution under the Horizon Europe Lump Sum Model Grant Agreement. Activities may include:

  • Research and development of advanced photonic devices and circuits
  • Integration of novel materials and architectures
  • Prototype fabrication and testing
  • System-level validation in representative application domains
  • Performance benchmarking and optimisation
  • Dissemination and exploitation activities

Funding conditions 

Type of action: 
Research and Innovation Actions (RIA) 

Funding rate: 
Up to 100% of total eligible costs 

EU contribution per project: 
Around EUR 5,000,000 - 6,000,000 

Number of funded projects: 
Up to 2 projects 

Project duration: 
Typically 36 months 

Deadline for submission

23 September 2027

Forthcoming
Company size: SMEs, Startups, Enterprises, Research, Academia
Issuer: European Health and Digital Executive Agency
Area: Food, Bioeconomy​, Agriculture
Call type: Research and Innovation Actions
Co-funding: Up to 100%
Date published: 20 April 2027
Deadline for submission: 23 September 2027